Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease
Nilesh Gajanan Bajad, Ravi Bhushan Singh, Gajendra T.A., Gopichand Gutti, Ashok Kumar, Sairam Krishnamurthy, Sushil Kumar Singh, Sushil Kumar Singh
Topics & Concepts
ChalconeChemistryAcetylcholinesteraseMoietyIn vivoPharmacologyPiperazineDocking (animal)Lead compoundLigand (biochemistry)BiochemistryStereochemistryIn vitroReceptorEnzymeOrganic chemistryMedicineNursingBiotechnologyBiologyCholinesterase and Neurodegenerative DiseasesComputational Drug Discovery MethodsSynthesis and biological activity