COVID-19 Vaccines: A Review of the Safety and Efficacy of Current Clinical Trials
Zhipeng Yan, Ming Yang, Ching‐Lung Lai
Abstract
Various strategies have been designed to contain the COVID-19 pandemic. Among them, vaccine development is high on the agenda in spite of the unknown duration of the protection time. Various vaccines have been under clinical trials with promising results in different countries. The protective efficacy and the short-term and long-term side effects of the vaccines are of major concern. Therefore, comparing the protective efficacy and risks of vaccination is essential for the global control of COVID-19 through herd immunity. This study reviews the most recent data of 12 vaccines to evaluate their efficacy, safety profile and usage in various populations.
Topics & Concepts
Coronavirus disease 2019 (COVID-19)MedicineHerd immunityPandemicClinical trialVaccine efficacyVaccination2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicineClinical efficacyVirologyOutbreakDiseaseInfectious disease (medical specialty)PathologyInternal medicineSARS-CoV-2 and COVID-19 ResearchVaccine Coverage and HesitancyAnimal Virus Infections Studies