Vitamin B12-peptide nucleic acids use the BtuB receptor to pass through the Escherichia coli outer membrane
Tomasz Pieńko, Jakub Czarnecki, Marcin Równicki, Monika Wojciechowska, Aleksandra J. Wierzba, Dorota Gryko, Dariusz Bartosik, Joanna Trylska
Abstract
transport system can be hijacked to enable PNA delivery to E. coli cells.
Topics & Concepts
Bacterial outer membraneEscherichia coliBiochemistryBiologyOligonucleotidePeriplasmic spaceChemistryPeptide nucleic acidPeptideCell biologyDNAGeneBacteriophages and microbial interactionsBacterial Genetics and BiotechnologyAdvanced biosensing and bioanalysis techniques