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Pharmacokinetics and Absorption, Distribution, Metabolism and Excretion of RGLS4326 in Mouse and Monkey, an Anti–miR-17 Oligonucleotide for the Treatment of Polycystic Kidney Disease

Amin Kamel, Tate Owen, Izaiah Cole, Tania Valencia, Edmund Lee

2023Drug Metabolism and Disposition13 citationsDOI

Topics & Concepts

PharmacokineticsKidneyExcretionPharmacologyCytochrome P450Drug metabolismIsozymeMetabolismBiologyChemistryRenal physiologyInternal medicineEndocrinologyBiochemistryEnzymeMedicineMicroRNA in disease regulationEpigenetics and DNA MethylationAdvanced biosensing and bioanalysis techniques
Pharmacokinetics and Absorption, Distribution, Metabolism and Excretion of RGLS4326 in Mouse and Monkey, an Anti–miR-17 Oligonucleotide for the Treatment of Polycystic Kidney Disease | Litcius