Tailoring surface stiffness to modulate senescent macrophage immunomodulation: Implications for osteo-/angio-genesis in aged bone regeneration
Yi Zhang, Jinjun Dai, Ruiyue Hang, Ruiyue Hang, Xiaohong Yao, Long Bai, Huaiyu Wang, Di Huang, Ruiqiang Hang, Ruiqiang Hang
Topics & Concepts
Mesenchymal stem cellSelf-healing hydrogelsMacrophageMacrophage polarizationBiomaterialRegeneration (biology)Cell biologyAngiogenesisChemistryImmune systemImmunologyCancer researchBiomedical engineeringMedicineBiologyIn vitroBiochemistryOrganic chemistryImmune cells in cancerMesenchymal stem cell researchExtracellular vesicles in disease