DNA methylation activates retron Ec86 filaments for antiphage defense
Yanjing Wang, Chen Wang, Zeyuan Guan, Jie Cao, Jia Xu, Shuangshuang Wang, Yongqing Cui, Qiang Wang, Yibei Chen, Yongqi Yin, Delin Zhang, Hongbo Liu, Ming Sun, Shuangxia Jin, Tao Pan, Tingting Zou
Abstract
). These findings provide insights into the retron Ec86 defense mechanism and underscore an emerging theme of antiphage defense through supramolecular complex assemblies.
Topics & Concepts
DNA methylationDNACell biologyMethylationBiologyGeneticsComputational biologyChemistryGeneGene expressionAutophagy in Disease and TherapyRNA modifications and cancerCRISPR and Genetic Engineering