Facile synthesis of a <i>C</i><sub>4</sub>-symmetrical inherently chiral calix[4]arene
Luke Hodson, Kevin J. Visagie, Michael‐Phillip Smith, Leigh Loots, David Kuter, Trégen M. Snayer, Gareth E. Arnott
Abstract
-Boc proline moiety allows for separation of the diastereomers formed, thus obtaining the pure enantiomers after hydrolysis. The enantiomers could be assigned based on the CD spectra and DFT calculated values.
Topics & Concepts
Combinatorial chemistryChemistryStereochemistryMaterials scienceNanotechnologySupramolecular Chemistry and ComplexesMolecular Sensors and Ion DetectionMolecular spectroscopy and chirality