The involvement of PI3K/Akt/mTOR/GSK3β signaling pathways in the antidepressant-like effect of AZD6765
Vivian B. Neis, Morgana Moretti, Priscila B. Rosa, Yasmim de Oliveira Dalsenter, Isabel Werle, Nicolle Platt, Fernanda Neutzling Kaufmann, Axel Fogaça Rosado, Matheus Henrique Besen, Ana Lúcia S. Rodrigues
Topics & Concepts
Tail suspension testPI3K/AKT/mTOR pathwayWortmanninPharmacologyChemistryAntidepressantProtein kinase BEndocrinologyContext (archaeology)Internal medicineBehavioural despair testMedicineHippocampusPhosphorylationSignal transductionBiologyBiochemistryPaleontologyTreatment of Major DepressionNeuroscience and Neuropharmacology ResearchTryptophan and brain disorders