Acidic Tumor Microenvironments and Emerging Therapeutic Strategies for Cancer Therapy
Yongzhi Zhuang, Liquan Tong, Xueying Sun
Abstract
exchangers. At present, none of the inhibitors targeting acidic TMEs have been approved for clinical use in cancer treatment, except for proton pump inhibitors that target V-ATPase. Development of highly specific agents and the discovery of more sensitive and precise biomarkers may help improve the effectiveness of these inhibitors for cancer therapy.
Topics & Concepts
Cancer therapyCancerMedicineOncologyCancer researchIntensive care medicineInternal medicineCancer, Hypoxia, and MetabolismATP Synthase and ATPases ResearchCancer Research and Treatments