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Silencing UHRF1 enhances cell autophagy to prevent articular chondrocytes from apoptosis in osteoarthritis through PI3K/AKT/mTOR signaling pathway

Xiaojuan Shi, Lei Han, Tianshu Sun, Feng Zhang, Shiying Ji, Min Zhang, Xiaoqing Wang, Weihong Yang

2020Biochemical and Biophysical Research Communications26 citationsDOI

Topics & Concepts

PI3K/AKT/mTOR pathwayAutophagyProtein kinase BCell biologyChondrocyteGene silencingApoptosisSignal transductionCell growthCancer researchRPTORBiologyChemistryCartilageAnatomyGeneticsGeneBiochemistryOsteoarthritis Treatment and MechanismsCancer-related molecular mechanisms researchChemokine receptors and signaling
Silencing UHRF1 enhances cell autophagy to prevent articular chondrocytes from apoptosis in osteoarthritis through PI3K/AKT/mTOR signaling pathway | Litcius