Increased Sparc release from subchondral osteoblasts promotes articular chondrocyte degeneration under estrogen withdrawal
Anlong Jiang, Peng Xu, Zhongwei Yang, Z. Zhao, Qiang Tan, Wei Li, Chunli Song, Hancheng Dai, Huijie Leng
Topics & Concepts
Subchondral boneChondrocyteDegeneration (medical)Articular cartilageEstrogenMedicineChemistryOsteoarthritisInternal medicineAnatomyCartilageOphthalmologyPathologyAlternative medicineOsteoarthritis Treatment and MechanismsBone Metabolism and DiseasesConnective Tissue Growth Factor Research