Acrolein produced by glioma cells under hypoxia inhibits neutrophil AKT activity and suppresses anti-tumoral activities
Hong‐Chieh Tsai, Zhen-Jie Tong, Tsong‐Long Hwang, Kuo‐Chen Wei, Pin‐Yuan Chen, Chiung-Yin Huang, Ko‐Ting Chen, Ya-Jui Lin, Hsiao-Wei Cheng, Hsiang‐Tsui Wang
Topics & Concepts
AcroleinGliomaChemistryImmune systemProinflammatory cytokineCancer researchTumor microenvironmentProtein kinase BHypoxia (environmental)ImmunologyInflammationBiologySignal transductionBiochemistryOrganic chemistryCatalysisOxygenImmune cells in cancerNeuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders