Association of Cervical Dysbacteriosis, HPV Oncogene Expression, and Cervical Lesion Progression
Hang Liu, Hua Liang, Di Li, Ming Wang, Yan Li
Abstract
The main findings of this study were that we clarified the associations of the different bacterial species with the expression of human papillomavirus (HPV) oncogenes at different stages of cervical cancer. Along with the severity of cervical lesions, the abundance of the genus and species of Lactobacillus obviously declined, while the aerobic and anaerobic bacteria, as well as the prevalence and expression of HPV E6/E7 oncogene, were increased dramatically.
Topics & Concepts
OncogeneCervical cancerMedicineLesionAssociation (psychology)OncologyPathologyInternal medicineBiologyCancerCell cyclePsychologyPsychotherapistCervical Cancer and HPV ResearchCancer-related molecular mechanisms researchReproductive tract infections research