Rapid decline in estimated glomerular filtration rate in sickle cell anemia: results of a multicenter pooled analysis
Kenneth I. Ataga, Qingning Zhou, Vimal K. Derebail, Santosh L. Saraf, Jane S. Hankins, Laura R. Loehr, Melanie E. Garrett, Allison E. Ashley‐Koch, Jianwen Cai, Marilyn J. Telen
Abstract
Chronic kidney disease (CKD), typically defined as kidney damage or decreased kidney function for 3 or more months, is common in sickle cell disease (SCD). 1 Increasing evidence suggests that the glomerulopathy of SCD is progressive. 2 CKD is associated with increased mortality in SCD. 5]
Topics & Concepts
Renal functionSickle cell anemiaMedicineAnemiaMulticenter studyInternal medicinePooled analysisUrologyMeta-analysisDiseaseRandomized controlled trialHemoglobinopathies and Related DisordersIron Metabolism and DisordersAutopsy Techniques and Outcomes