Single-Cell Analysis of Crohn’s Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy

J.P. Martin, Christie Chang, Gilles Boschetti, Ryan C. Ungaro, Mamta Giri, John A. Grout, Kyle Gettler, Ling-Shiang Chuang, Shikha Nayar, Alexander J. Greenstein, Marla C. Dubinsky, Laura Walker, Andrew M. Leader, Jay S. Fine, Charles E. Whitehurst, M. Lamine Mbow, Subra Kugathasan, Lee A. Denson, Jeffrey S. Hyams, Joshua R. Friedman, Prerak Desai, Huaibin M. Ko, Ilaria Laface, Güray Aktürk, Eric E. Schadt, Hélène Salmon, Sacha Gnjatic, Adeeb Rahman, Miriam Mérad, Judy H. Cho, Ephraim Kenigsberg