Optimization of pretreatment methods for cerebrospinal fluid metabolomics based on ultrahigh performance liquid chromatography/mass spectrometry
Zhiqiang Song, Mian Wang, Zhenyu Zhu, Gusheng Tang, Yue Liu, Yifeng Chai
Topics & Concepts
ChemistryChromatographyProtein precipitationMetabolomicsHydrophilic interaction chromatographyMass spectrometrySample preparationHigh-performance liquid chromatographyCerebrospinal fluidQuantitative analysis (chemistry)SolventBiochemistryMedicinePathologyMetabolomics and Mass Spectrometry StudiesCancer, Hypoxia, and MetabolismAnalytical Chemistry and Chromatography