The Inactivated ISKNV-I Vaccine Confers Highly Effective Cross-Protection against Epidemic RSIV-I and RSIV-II from Cultured Spotted Sea Bass Lateolabrax maculatus
Weixuan Fu, Yong Li, Yuting Fu, Wenfeng Zhang, Panpan Luo, Qianqian Sun, Fangzhao Yu, Shaoping Weng, Wangdong Li, Jianguo He, Chuanfu Dong
Abstract
Red seabream iridovirus (RSIV) infects a wide mariculture bony fish and has resulted in significant annual economic loss worldwide. Previous studies showed that the phenotypic diversity of infectious RSIV isolates would lead to different virulence characteristics, viral antigenicity, and vaccine efficacy as well as host range.
Topics & Concepts
BiologyIridovirusVirologyVirusAquaculture disease management and microbiotaAnimal Virus Infections StudiesVirus-based gene therapy research