Recent Advances in Palladium‐Catalyzed Asymmetric Heck/Tsuji–Trost Reactions of 1,n‐Dienes
Guofeng Zhao, Wenbo Li, Junliang Zhang
Abstract
Transition-metal catalyzed tandem asymmetric reactions were powerful tools to access various chiral compounds. Many strategies have been developed for the coupling of 1,n-dienes with aryl halides via a tandem Heck/Tsuji-Trost process. However, the control of regio- and stereo-chemistry remains a challenging task. This minireview details the recent advances in the field of asymmetric Heck/Tsuji-Trost reactions catalyzed by palladium complex, which have opened new opportunities and expanded our understanding in this area of research in recent years.
Topics & Concepts
PalladiumHeck reactionCatalysisChemistryTandemArylTsuji–Trost reactionHalideCombinatorial chemistryOrganic chemistryMaterials scienceComposite materialAlkylCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and CatalysisAsymmetric Synthesis and Catalysis