Litcius/Paper detail

Activation of STING by targeting a pocket in the transmembrane domain

Defen Lu, Guijun Shang, Jie Li, Yong Lu, Xiao‐chen Bai, Xuewu Zhang

2022Nature181 citationsDOIOpen Access PDF

Topics & Concepts

StingStimulator of interferon genesTransmembrane proteinDimerOligomerConformational changeTransmembrane domainLigand (biochemistry)ChemistryCell biologyBiophysicsInnate immune systemBiologyStereochemistryBiochemistryReceptorOrganic chemistryEngineeringAerospace engineeringinterferon and immune responsesImmune Response and InflammationViral Infections and Vectors