Extraction-free RT-LAMP to detect SARS-CoV-2 is less sensitive but highly specific compared to standard RT-PCR in 101 samples
John J. Schellenberg, Margaret Ormond, Yoav Keynan
Topics & Concepts
Loop-mediated isothermal amplificationSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)False positive paradoxMedicinePoint-of-care testingCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakPrimer (cosmetics)VirologyInternal medicineBiologyPathologyStatisticsDNAChemistryMathematicsGeneticsInfectious disease (medical specialty)DiseaseOutbreakOrganic chemistrySARS-CoV-2 detection and testingBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniques