Switchable and dynamic G-quadruplexes and their applications
Jiantong Dong, Michael O’Hagan, Itamar Willner
Abstract
nanoparticles or metal-organic framework nanoparticles, yields stimuli-responsive materials exhibiting shape-memory, self-healing, and controlled drug release properties. Indeed, G-quadruplex-modified nanomaterials find growing interest in the area of nanomedicine. Beyond the impressive G-quadruplex-based scientific advances achieved to date, exciting future developments are still anticipated. The review addresses these goals by identifying the potential opportunities and challenges ahead of the field in the coming years.
Topics & Concepts
Control reconfigurationNanotechnologyG-quadruplexChemistryComputer scienceBiochemical engineeringComputational biologyMaterials scienceEngineeringBiologyBiochemistryDNAEmbedded systemAdvanced biosensing and bioanalysis techniquesDNA and Nucleic Acid ChemistryMolecular Junctions and Nanostructures