Pliable, Scalable, and Degradable Scaffolds with Varying Spatial Stiffness and Tunable Compressive Modulus Produced by Adopting a Modular Design Strategy at the Macrolevel
Hailong Liu, Shubham Jain, Astrid Ahlinder, Tiziana Fuoco, Thomas C. Gasser, Anna Finne‐Wistrand
Abstract
experiments, it was observed that the addition of knitted mesh and an electrospun nanofiber layer to the scaffold significantly increased cell seeding efficiency, cell attachment, and proliferation compared to the 3D-printed scaffold alone. In summary, our results suggest that the proposed design strategy is promising for soft tissue engineering of scaffolds to assist breast reconstruction and regeneration.
Topics & Concepts
Materials scienceScaffoldStiffnessFinite element methodUltimate tensile strengthComposite materialStiffeningNanofiberBiomedical engineeringStructural engineeringEngineeringBone Tissue Engineering MaterialsElectrospun Nanofibers in Biomedical ApplicationsAdditive Manufacturing and 3D Printing Technologies