Lyophilized Amorphous Dispersion of Telmisartan in a Combined Carrier–Alkalizer System: Formulation Development and <i>In Vivo</i> Study
Khater AL-Japairai, Hala M. Alkhalidi, Syed Mahmood, Samah Hamed Almurisi, Abd Almonem Doolaanea, Taha A. Al-Sindi, Bappaditya Chatterjee
Abstract
dissolution and improve oral bioavailability.
Topics & Concepts
BioavailabilityTelmisartanDissolutionDifferential scanning calorimetryAmorphous solidFourier transform infrared spectroscopySolubilityMaterials scienceAqueous solutionNuclear chemistryChemistryChromatographyDissolution testingChemical engineeringOrganic chemistryPharmacologyMedicineBiopharmaceutics Classification SystemBlood pressureRadiologyEngineeringPhysicsThermodynamicsDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsProtein purification and stability