Litcius/Paper detail

Mechanisms of insulin resistance, mitochondrial dysfunction and the action of the ketogenic diet in bipolar disorder. Focus on the PI3K/AKT/HIF1-a pathway

Iain H. Campbell, Harry Campbell

2020Medical Hypotheses59 citationsDOI

Topics & Concepts

Insulin resistanceHyperinsulinemiaPI3K/AKT/mTOR pathwayKetogenic dietBipolar disorderProtein kinase BPyruvate dehydrogenase complexMedicineInsulin receptorEndocrinologyInternal medicineInsulinSignal transductionBiologyEpilepsyPsychiatryEnzymeGeneticsBiochemistryLithium (medication)Diet and metabolism studiesBipolar Disorder and TreatmentPancreatic function and diabetes