Targeting cariogenic pathogens and promoting competitiveness of commensal bacteria with a novel pH-responsive antimicrobial peptide
Wentao Jiang, Zhuo Xie, Shuheng Huang, Qiting Huang, Lingling Chen, Xianling Gao, Zhengmei Lin
Abstract
production of the commensal bacteria and subsequently improved the ecological competitiveness of the commensals. The dual-functional mechanism made LH12 a potential bioresponsive approach to caries management.
Topics & Concepts
Streptococcus gordoniiBiofilmMicrobiologyMicroecologyStreptococcus mutansDysbiosisVirulenceAntimicrobialBacteriaBiologyMicrobiomeCommensalismChemistryBiochemistryGeneBioinformaticsGeneticsOral microbiology and periodontitis researchAntimicrobial Peptides and ActivitiesBacterial biofilms and quorum sensing