Microenvironmental ammonia enhances T cell exhaustion in colorectal cancer
Hannah N. Bell, Amanda K. Huber, Rashi Singhal, Navyateja Korimerla, Ryan J. Rebernick, Roshan Kumar, Marwa O. El-Derany, Peter Sajjakulnukit, Nupur K. Das, Samuel A. Kerk, Sumeet Solanki, Jadyn G. James, Donghwan Kim, Li Zhang, Brandon Chen, Rohit Mehra, Timothy L. Frankel, Balázs Győrffy, Eric R. Fearon, Marina Pasca di Magliano, Frank J. Gonzalez, Ruma Banerjee, Daniel Wahl, Costas A. Lyssiotis, Michael J. Green, Yatrik M. Shah
Topics & Concepts
Cancer researchColorectal cancerTumor microenvironmentReprogrammingImmune systemImmunotherapyAmmoniaCancerBiologyCellMedicineImmunologyInternal medicineTumor cellsBiochemistryCancer, Hypoxia, and MetabolismImmune cells in cancerFerroptosis and cancer prognosis