Regulation of Toll-like receptor-mediated inflammatory response by microRNA-152-3p-mediated demethylation of MyD88 in systemic lupus erythematosus
Bei Tao, Wei Xiang, Xianglong Li, Chengsong He, Ligang Chen, Xiangguo Xia, Tangming Peng, Lilei Peng, Xiaobo Yang, Chuanhong Zhong
Topics & Concepts
ImmunologyDNMT1microRNAGene silencingPathogenesisDNA methylationImmune systemInflammationPeripheral blood mononuclear cellBiologyToll-like receptorDNA methyltransferaseLupus erythematosusCD40Cancer researchAntibodyInnate immune systemGene expressionIn vitroCytotoxic T cellGeneBiochemistryImmune Response and Inflammationinterferon and immune responsesMicroRNA in disease regulation