Integrated in silico and in vitro discovery of a new anticancer thiadiazole analog targeting VEGFR-2
Ibrahim H. Eissa, Hazem Elkady, Walid E. Elgammal, Hazem A. Mahdy, Eslam B. Elkaeed, Aisha A. Alsfouk, Ibrahim M. Ibrahim, Dalal Z. Husein, Ahmed M. Metwaly
Topics & Concepts
ChemistryIn silicoApoptosisIn vitroCytotoxicityDocking (animal)Cell cycleSorafenibCell cultureCell cycle checkpointCell growthCancer researchPharmacologyBiochemistryGeneBiologyHepatocellular carcinomaGeneticsMedicineNursingSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Characterization of Heterocyclic Compounds