Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo
Zhongwei Liu, Neal Shah, Kent L. Marshall, Samuel A. Sprowls, Pushkar Saralkar, Afroz S. Mohammad, Kathryn E. Blethen, Tasneem Arsiwala, Ross Fladeland, Paul R. Lockman, Weimin Gao
Topics & Concepts
GefitinibIn vivoBrain metastasisMTT assayCisplatinLung cancerIn vitroPharmacologyMedicineEpidermal growth factor receptorCancer researchWestern blotMetastasisChemistryCancerBiologyChemotherapyOncologyInternal medicineBiochemistryGeneBiotechnologyLung Cancer Treatments and MutationsLung Cancer Research StudiesQuinazolinone synthesis and applications