Fitusiran prophylaxis in people with severe haemophilia A or haemophilia B without inhibitors (ATLAS-A/B): a multicentre, open-label, randomised, phase 3 trial
Alok Srivastava, Savita Rangarajan, Kaan Kavaklı, Robert Klamroth, Gili Kenet, Liane Khoo, Chur-Woo You, Weiqun Xu, Niel Malan, Laurent Frenzel, Catherine Bagot, Oleksandra Stasyshyn, Chia-Yau Chang, Stacey Poloskey, Zhiying Qiu, Shauna Andersson, Baisong Mei, Steven W. Pipe
Topics & Concepts
MedicineHaemophiliaClotting factorTolerabilityHaemophilia BHaemophilia AClinical endpointAdverse effectPediatricsInternal medicineClinical trialIntention-to-treat analysisSurgeryHemophilia Treatment and ResearchBlood Coagulation and Thrombosis MechanismsCoagulation, Bradykinin, Polyphosphates, and Angioedema