Exploring the interaction of tepotinib with calf thymus DNA using molecular dynamics simulation and multispectroscopic techniques
Mohd Amir, M. A. Qureshi, Ashma Khan, Shahid M. Nayeem, Waseem Ayoub Malik, Saleem Javed
Topics & Concepts
ChemistryBinding constantIn silicoMolecular dynamicsDNATyrosine-kinase inhibitorQuenching (fluorescence)BiophysicsBinding siteCancerFluorescenceBiochemistryGeneComputational chemistryInternal medicineBiologyMedicinePhysicsQuantum mechanicsMetal complexes synthesis and propertiesDNA and Nucleic Acid ChemistryCancer therapeutics and mechanisms