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Design, synthesis, spectroscopic characterization, in vitro tyrosinase inhibition, antioxidant evaluation, in silico and kinetic studies of substituted indole-carbohydrazides

Aida Iraji, Negar Sheikhi, Mahshid Attarroshan, Gholam Reaz Sharifi Ardani, Maryam Kabiri, Ali Naghibi Bafghi, Farzad Kobarfard, Zahra Rezaei, Mehdi Khoshneviszadeh, Alireza Foroumadi, Seyedeh Sara Mirfazli

2022Bioorganic Chemistry34 citationsDOI

Topics & Concepts

ChemistryADMETyrosinaseStereochemistryProton NMRIn silicoIndole testDocking (animal)IC50Lead compoundCarbon-13 NMRSubstituentEnzymeIn vitroBiochemistryGeneMedicineNursingmelanin and skin pigmentationBiochemical Analysis and Sensing TechniquesSkin Protection and Aging
Design, synthesis, spectroscopic characterization, in vitro tyrosinase inhibition, antioxidant evaluation, in silico and kinetic studies of substituted indole-carbohydrazides | Litcius