Design, synthesis, spectroscopic characterization, in vitro tyrosinase inhibition, antioxidant evaluation, in silico and kinetic studies of substituted indole-carbohydrazides
Aida Iraji, Negar Sheikhi, Mahshid Attarroshan, Gholam Reaz Sharifi Ardani, Maryam Kabiri, Ali Naghibi Bafghi, Farzad Kobarfard, Zahra Rezaei, Mehdi Khoshneviszadeh, Alireza Foroumadi, Seyedeh Sara Mirfazli
Topics & Concepts
ChemistryADMETyrosinaseStereochemistryProton NMRIn silicoIndole testDocking (animal)IC50Lead compoundCarbon-13 NMRSubstituentEnzymeIn vitroBiochemistryGeneMedicineNursingmelanin and skin pigmentationBiochemical Analysis and Sensing TechniquesSkin Protection and Aging