Stress Induces Dynamic, Cytotoxicity-Antagonizing TDP-43 Nuclear Bodies via Paraspeckle LncRNA NEAT1-Mediated Liquid-Liquid Phase Separation
Chen Wang, Yongjia Duan, Gang Duan, Qiangqiang Wang, Kai Zhang, Xue Deng, Beituo Qian, Jinge Gu, Zhiwei Ma, Shuang Zhang, Lin Guo, Cong Liu, Yanshan Fang
Topics & Concepts
Stress granuleBiologyCell biologyCytoplasmDownregulation and upregulationCytotoxicityNeurodegenerationChromosomal translocationIn vitroBiophysicsBiochemistryPathologyTranslation (biology)GeneMessenger RNADiseaseMedicineRNA Research and SplicingAmyotrophic Lateral Sclerosis ResearchRNA modifications and cancer