Litcius/Paper detail

Too much water drowned the miller: Akkermansia determines immunotherapy responses

Le Li, Florencia McAllister

2022Cell Reports Medicine15 citationsDOIOpen Access PDF

Abstract

demonstrated that intestinal Akkermansia muciniphila predicts vigorous response to immunotherapy in non-small-cell lung cancer. Baseline level of this microbe has better value than PD-L1 expression and represents a unique approach for stratifying patients that can benefit from immunotherapy.

Topics & Concepts

MillerMedicineBiologyEcologyImmune Cell Function and InteractionImmunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers