Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite
Gabriele Cerutti, Yicheng Guo, Tongqing Zhou, Jason Gorman, Myungjin Lee, Micah Rapp, Eswar R. Reddem, Jian Yu, Fabiana Bahna, Jude Bimela, Yaoxing Huang, Phinikoula S. Katsamba, Lihong Liu, Manoj S. Nair, Reda Rawi, Adam S. Olia, Pengfei Wang, Baoshan Zhang, Gwo‐Yu Chuang, David D. Ho, Zizhang Sheng, Peter D. Kwong, Lawrence Shapiro
Topics & Concepts
AntibodyEpitopeBiologyGlycanVirologyNeutralizing antibodySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)NeutralizationSingle-domain antibodySpike ProteinCoronavirus disease 2019 (COVID-19)Molecular biologyGlycoproteinImmunologyMedicineInfectious disease (medical specialty)DiseasePathologySARS-CoV-2 and COVID-19 ResearchBacteriophages and microbial interactionsViral gastroenteritis research and epidemiology