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COVID-19: Post-vaccine Smell and Taste Disorders: Report of 6 Cases

Jérôme R. Lechien, Alpha Oumar Karim Diallo, Bernard Dachy, Serge D. Le Bon, Antonino Maniaci, Luigi Angelo Vaira, Sven Saussez

2021Ear Nose & Throat Journal39 citationsDOIOpen Access PDF

Abstract

Post-vaccine olfactory and gustatory disorders are very rare and were reported in patients who received influenza vaccines. In this article, we report 6 cases of post-coronavirus disease 2019 (COVID-19) vaccine olfactory and gustatory disorders in patients with negative nasal swabs. Precisely, olfactory and gustatory dysfunctions were reported in 5 and 1 patients, respectively. Sense disorders occurred after the first injection of AstraZeneca (n = 4) or the second injection of Pfizer (n = 2) vaccines. In 4 cases, the olfactory or gustatory disorder was confirmed with psychophysical evaluations. The duration of chemosensory dysfunction ranged from 4 to 42 days. None of the patient reported mid- or long-term olfactory or gustatory disorder. The occurrence of olfactory and gustatory dysfunctions in adults benefiting from COVID-19 vaccines is still rare but has to be known by otolaryngologists.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)TasteAnosmiaMedicineOlfactionTaste disorderSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakOlfactory systemNasal administrationDiseaseAudiologyVirologyInternal medicinePsychiatryPsychologyNeuroscienceInfectious disease (medical specialty)OutbreakSARS-CoV-2 and COVID-19 ResearchPeripheral Neuropathies and DisordersOlfactory and Sensory Function Studies
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