Thermal Behavior of Mg-Doped Calcium-Deficient Apatite and Stabilization of β Tricalcium Phosphate
Asmaa Massit, Ahmed El Yacoubi, A. Rezzouk, Brahim Chafik El Idrissi, El Idrissi, F Zou, N Zhao, X Fu, J Diao, Y Ma, X Cao, S Wan, S Zhong, Y Wang, Jorge Chanfrau, Jorge Chanfrau, Yaymarilis Veranes Pantoja, Antonio Guastaldi, D Ke, S Bose, S Tkachenko, M Horynov, M Casas-Luna, S Diaz-De-La-Torre, K Dvok, L Celko, J Kaiser, E Montufar, M Motisuke, G Mestres, C Ren, R O; Carrodeguas, C Zavaglia, P Ginebra, A Altomare, R Rizzi, M Rossi, A El Khouri, M Elaatmani, V Paterlini, G Ventura, Capitelli, I Mayer, F Cuisinier, S Gdalya, I Popov, S Kannan, I Lemos, J Rocha, J Ferreira, G Cheng, C Deng, C Wu, H Yin, Y Ruan, Y Sun, Q Xie, X Wu, M Frasnelli, V Sglavo, M Zhang, C Wu, H Li, J Yuen, J Chang, Y Xiao, E Boanini, M Gazzano, C Nervi, M Chierotti, K Rubini, R Gobetto, A Bigi, M Sader, V Martins, S Gomez, R Legeros, G Soares, M Nabiyouni, T Bruckner, H Zhou, U Gbureck, S Bhaduri, L Cao, I Ullah, N Li, S Niu, R Sun, D Xia, R Yang, X Zhang, J Cooke, D Losordo, A Romani, Y Gu, J Zhang, X Zhang, G Liang, T Xu, W Niu
Abstract
β-tricalcium phosphate (β-TCP) is a bioceramic with unique osteoinductive and osteoconductive properties. It can be obtained by calcining calcium-deficient apatites (CDHA) at 750°C and above. The reduction of calcining temperature or the stabilization of the β phase, by doping, is therefore of particular interest. This paper investigates the preparation of CDHA with a theoretical 0.05 Mg/(Ca + Mg) ratio and (Ca+Mg)/P = 1.55 via precipitation method, and the resultant powder is calcined at a different temperature ranging from 80 to 715°C. The as-synthesized undoped powder was used as the reference in this study. The effect of calcination temperature and composition were investigated by the aid of X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), inductively coupled plasma optical emission spectroscopy (ICP-OES) and scanning electron microscopy (SEM). The study indicated that the powder was pure Mg-doped beta-tricalcium phosphate. The incorporation of Mg within the calcium phosphate lattice promoted the formation and stabilization of the β -TCP phase at a lower temperature.