(E)-N-(3-chlorophenyl)-1-(5-nitro-2-(piperidin-1-yl)phenyl)methanimine: X-Ray, DFT, ADMET, Boiled-Egg Model, Druggability, Bioavailabilty, and Human Cyclophilin D (CypD) Inhibitory Activity
Songül Şahin, Necmi Dege
Topics & Concepts
ChemistryLipinski's rule of fiveDocking (animal)DruggabilityAutoDockStereochemistryADMEHOMO/LUMOHydrogen bondComputational chemistryMoleculeIn silicoOrganic chemistryBiochemistryIn vitroGeneNursingMedicineComputational Drug Discovery MethodsSynthesis of Tetrazole DerivativesSynthesis and bioactivity of alkaloids