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RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

Wei Wu, Rahul Bhowmick, Ivan Vogel, Özgün Özer, Fiorella Ghisays, Roshan Singh Thakur, Esther León, P. Richter, Liqun Ren, John H.J. Petrini, Ian D. Hickson, Ying Liu

2020Nature Structural & Molecular Biology94 citationsDOI

Topics & Concepts

BiologyGeneticsHelicaseGenomeTelomereDNA replicationLocus (genetics)DNAGeneRNACRISPR and Genetic EngineeringDNA Repair MechanismsGenomics and Chromatin Dynamics
RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome | Litcius