Mesoporous Silica Nanoparticles Improve Oral Delivery of Antitubercular Bicyclic Nitroimidazoles
Ang Chee Wei, Lendl Tan, Zhi Qu, Nicholas P. West, Matthew A. Cooper, Amirali Popat, Mark A. T. Blaskovich
Abstract
) compared to MCC7433 alone. The current work highlights the potential of using nanoparticles such as mesoporous silica as a carrier for oral delivery of poorly soluble antibacterial agents against tuberculosis.
Topics & Concepts
Mesoporous silicaNanoparticleBicyclic moleculeMaterials scienceNanotechnologyMesoporous materialChemistryOrganic chemistryCatalysisDrug Solubulity and Delivery SystemsAdvanced Drug Delivery SystemsNanoparticle-Based Drug Delivery