Use of CRISPR-based screens to identify mechanisms of chemotherapy resistance
George Alyateem, Heidi M. Wade, Aaron A. Bickert, Crystal C. Lipsey, Priya Mondal, MacKinzie D. Smith, Rania M. Labib, Beverly A. Mock, Robert W. Robey, Michael M. Gottesman
Topics & Concepts
CRISPRDrug resistanceMechanism (biology)CancerComputational biologyDrug discoveryDrugSynthetic lethalityBiologyBioinformaticsGeneMedicinePharmacologyGeneticsDNA repairPhilosophyEpistemologyCRISPR and Genetic EngineeringCAR-T cell therapy researchCancer Mechanisms and Therapy