Indoleamine 2, 3-dioxygenase 1 activation in macrophage exacerbates hepatic ischemia-reperfusion injury by triggering hepatocyte ferroptosis
Shuoyi Ma, Junjie Li, Haixin Ye, Chaofeng Wu, Jia Zhang, Shu Xu, Yuhong Song, Yong Gu, Lei Gao
Topics & Concepts
Indoleamine 2,3-dioxygenaseEfferocytosisReperfusion injuryLiver injuryMedicineIschemiaMacrophage polarizationImmunologyInflammationHepatocyteTransplantationLiver transplantationCancer researchPharmacologyMacrophageBiologyInternal medicineIn vitroBiochemistryAmino acidTryptophanFerroptosis and cancer prognosisTryptophan and brain disordersImmune cells in cancer