New spiropyrrolothiazole derivatives bearing an oxazolone moiety as potential antidiabetic agent: Design, synthesis, crystal structure, Hirshfeld surface analysis, ADME and molecular docking studies
Manel Ben Hammouda, Sarra Boudriga, Khaled Hamden, Moheddine Askri, Michael Knorr, Carsten Strohmann, Lukas Brieger, Anna Krupp, El Hassane Anouar, Mejdi Snoussi, Kaïss Aouadi, Adel Kadri
Topics & Concepts
ChemistryStereochemistryIC50MoietyCrystal structureADMEBiochemistryOrganic chemistryIn vitroSynthesis and biological activitySynthesis and Reactions of Organic CompoundsSynthesis of heterocyclic compounds