Dorsal root ganglion toxicity after AAV intra-CSF delivery of a RNAi expression construct into non-human primates and mice
Zachary C. E. Hawley, Ingrid D. Pardo, Shaolong Cao, Maria I. Zavodszky, Fergal Casey, Kyle Ferber, Yi Luo, Sam Hana, Shukkwan K. Chen, Jessica Doherty, Raquel Costa, Patrick Cullen, Yuqing Liu, Thomas M. Carlile, Twinkle Chowdhury, Benjamin Doyle, Pete Clarner, Kevin Mangaudis, Edward Guilmette, Shawn Bourque, David Koske, Murali V.P. Nadella, Patrick Trapa, Michael L. Hawes, Denitza Raitcheva, Shih‐Ching Lo
Topics & Concepts
Dorsal root ganglionRNA interferenceBiologyDorsumToxicityCell biologyConstruct (python library)PharmacologyMedicineAnatomyGeneRNAInternal medicineGeneticsComputer scienceProgramming languageVirus-based gene therapy researchRNA Interference and Gene DeliveryNanoplatforms for cancer theranostics