HIF-1α induced by hypoxic condition regulates Treg/Th17 axis polarization in chronic immune thrombocytopenia
Hao Gu, Zhifa Wang, Xingjuan Xie, Hui Chen, Juntao Ouyang, Runhui Wu, Zhenping Chen, Zhenping Chen
Topics & Concepts
FOXP3PathogenesisDownregulation and upregulationImmune systemImmune thrombocytopeniaMedicineImmunologyHypoxia (environmental)Hypoxia-inducible factorsPlateletAutoimmunityImmune toleranceInternal medicineGeneBiologyChemistryGeneticsOxygenOrganic chemistryPlatelet Disorders and TreatmentsBlood groups and transfusionHematopoietic Stem Cell Transplantation