Litcius/Paper detail

Sigma profiles in deep learning: towards a universal molecular descriptor

Dinis O. Abranches, Yong Zhang, Edward J. Maginn, Yamil J. Colón

2022Chemical Communications62 citationsDOIOpen Access PDF

Abstract

This work showcases the remarkable ability of sigma profiles to function as molecular descriptors in deep learning. The sigma profiles of 1432 compounds are used to train convolutional neural networks that accurately correlate and predict a wide range of physicochemical properties. The architectures developed are then exploited to include temperature as an additional feature.

Topics & Concepts

SigmaConvolutional neural networkDeep learningArtificial intelligenceFeature (linguistics)Function (biology)Range (aeronautics)Computer sciencePattern recognition (psychology)Biological systemMaterials sciencePhysicsBiologyQuantum mechanicsPhilosophyComposite materialEvolutionary biologyLinguisticsComputational Drug Discovery MethodsMachine Learning in Materials ScienceCrystallography and molecular interactions