Sub-attomole detection of HIV-1 using padlock probes and rolling circle amplification combined with microfluidic affinity chromatography
Ruben R. G. Soares, João Varela, Ujjwal Neogi, Sibel Ciftci, Manickam Ashokkumar, Inês F. Pinto, Mats Nilsson, Narayanan Madaboosi, Aman Russom
Topics & Concepts
Rolling circle replicationDetection limitFluorophoreNucleaseNASBAHuman immunodeficiency virus (HIV)MicrofluidicsChromatographyBiologyComputational biologyNanotechnologyChemistryFluorescenceVirologyMaterials scienceDNAPhysicsGeneticsOpticsNucleic acid sequenceDNA replicationAdvanced biosensing and bioanalysis techniquesHIV Research and TreatmentBiosensors and Analytical Detection