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Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation

Young-Sik Cho, Sreerupa Challa, David Moquin, Ryan M. Genga, Tathagat Dutta Ray, Melissa Guildford, Francis Ka-Ming Chan

2009Cell2,406 citationsDOIOpen Access PDF

Topics & Concepts

BiologyPhosphorylationInflammationCell biologyApoptosisNecrosisTumor necrosis factor alphaVirusVirologyBiochemistryImmunologyGeneticsCell death mechanisms and regulationInflammasome and immune disordersinterferon and immune responses
Phosphorylation-Driven Assembly of the RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation | Litcius