Structures of human bile acid exporter ABCB11 reveal a transport mechanism facilitated by two tandem substrate-binding pockets
Liang Wang, Wen-Tao Hou, Jie Wang, Da Xu, Cong Guo, Linfeng Sun, Ke Ruan, Cong-Zhao Zhou, Yuxing Chen
Topics & Concepts
BiologyMechanism (biology)Bile acidBiochemistryTandemCell biologyPlasma protein bindingTransport proteinPeptide sequenceComputational biologyTandem repeatDrug Transport and Resistance MechanismsPediatric Hepatobiliary Diseases and TreatmentsTrace Elements in Health