Programming tumor evolution with selection gene drives to proactively combat drug resistance
Scott M. Leighow, Joshua Reynolds, Ivan Sokirniy, Shun Yao, Zeyu Yang, Haider Inam, Dominik Wodarz, Marco Archetti, Justin R. Pritchard
Topics & Concepts
Selection (genetic algorithm)GeneGene selectionComputational biologyBiologyDrug resistanceProdrugComputer scienceGeneticsGene expressionPharmacologyMachine learningMicroarray analysis techniquesCancer Genomics and DiagnosticsEvolution and Genetic DynamicsCRISPR and Genetic Engineering